MAJOR CATEGORIES OF PSYCHIATRIC DISORDER: Psychoses=the schizophrenias What is usually meant by CRAZY Hallucinations and delusions are common i. Especially "voices", auditory hallucinations As is DISORGANIZATION of thought and behavior i. Examples ii. Meaning of the term "schizophrenia" Problem: the manias OFTEN mimic schiziform thought disorders Affective (emotional) disorders: Depression - the mood disorders i. Generally distinguish between depression alternating with manic episodes, or "bipolar" depression, and just plain depressed. Anxiety - Many forms of excessive anxiety: i. Panic attacks ii. Phobias, especially Social phobia iii. Obsessive-compulsive disorder Social Misbehavior Hyperactivity Anti-social Personality Substance Abuse ETIOLOGY: THE CAUSES OF MENTAL DISORDER THE PROBLEM: NATURE OR NURTURE? DEMONSTRATING HERITABILITY DOES NOT RULE OUT AN ENVIRONMENTAL CAUSE DEMONSTRATED RESPONSE TO DRUGS DOES NOT RULE OUT AN ENVIRONMENTAL CAUSE DEMONSTRATING A BRAIN LESION IN A DISORDER DOES NOT RULE OUT AN ENVIRONMENTAL CAUSE THE CONVERSE IS ALSO TRUE: Lack of a known genetic predisposition, coupled with no known brain lesion and no response to known drugs may simply be a measure of ignorance ONLY IDENTIFICATION OF: What is wrong in the brain The necessary conditions which produce this abnormality CAN DETERMINE ETIOLOGY EPIDEMIOLOGY: THE PREVALENCE OF MENTAL DISORDERS: EPIDEMIOLOGY: Who gets a disease, how frequently THE PSYCHOSES: Earlier, worse in males Uncertain class differences Somewhere between 1% and 2%, world-wide Cost in US estimated around $ 65 billion/year DEPRESSION: Unipolar depression: Common, about 17% experience in a lifetime Chronic and recurring, about 10% experienced in the last year Twice as likely in women Bi-polar depression: Much less common, around 1%, incidence same over sexes ANXIETY DISORDERS: MOST common, although the line between normal and abnormal/dysfunctional is VERY hard to draw Is a fear of public speaking included? What about arachnaphobia? Fear of heights? "Simple" phobias, such as above, are VERY common, around 14% of women, 8% of males Panic attack/agoraphobia: A crippling disorder, leaves people house-bound; incidence around 4%, and more women affected Obsessive-compulsive disorder: Obsessive, anxiety- provoking thoughts treated with compulsive behavior - lifetime incidence around 2.5%, no sex difference COMORBIDITY: The clinical reality: about 15% of US population suffers from MULTIPLE disorders, is functionally crippled