Dr. Michaelann Tartis

Dr. Michaelann S. Tartis
Dual Appointment: Associate Professor of Chemical Engineering, Materials Engineering
Adjunct Faculty of Biology
Phone: 575-835-5761
Fax: 575-835-5210
Email: mstartis@nmt.edu

Education

Ph.D. - Biomedical Engineering - University of California at Davis
B.S. - Chemical Engineering - New Mexico Tech

Research Experience

New Mexico Tech
Associate Professor (August 2007 - present)

UC Davis Center for Molecular and Genomic Imaging
Postdoctoral Researcher (October 2006 - August 2007)

Sandia National Lab
Intern (May 2001 - August 2002)

Research Interests

*Synthesis, formulation and testing of various custom lipid-based drug delivery vehicles
*Coordinating complex experiments involving extensive interdisciplinary efforts, numerous individuals, and multi-imaging modalities
*Targeted drug delivery and imaging research including ultrasound, PET, CT and optical techniques both in vitro and in vivo
*Biosensor development utilizing whole cell encapsulation
*Partial patent owner titled, "Ultrasonic Concentration of Drug Delivery Capsules"

Teaching Experience

*BIO 189 Bioengineering LLC: Designing a wiresless sensor to monitor equine physiology
*ChE 189 Futures in Chemical Engineering: Introduction to engineering skills, programs, calculations
*ChE 326 Principles of Chemical Engineering: Chemical processes, material and energy balances
*ChE 443 Process Dynamics and Control: Control theory and design as it applies to chemical processes
*ChE 443L Process Dynamics and Control Lab: Hands on and simulations laboratory
*ChE 485 Senior Seminar: Soft engineering skills, communication, presentations, professionalism
*MATE 576/ ChE 476 Biomaterials - Drug Delivery: Hands-on demos & analysis of biomat techniques
*MATE 599/ChE 489 Bioinspired Design: Interdisciplinary design course using "Life's Principles"

Publications

Johnston R, Rogelj S, Harper JC, Tartis M. Sol-Generating Chemical Vapor into Liquid (SG-CViL) Deposition- A Facile Method for Encapsulation of Diverse Cell Types in Silica Matrices. J Mater Chem B Mater Biol Med. 2015 Feb 14;3(6):1032-1041.

Mikhalin AA, Evdokimov NM, Frolova LV, Magedov IV, Kornienko A, Johnston R, Rogelj S, Tartis MS. Lipophilic prodrug conjugates allow facile and rapid synthesis of high-loading capacity liposomes without the need for post-assembly purification. J Liposome Res. 2014 Dec 23:1-29.

Harper JC, Lopez DM, Larkin EC, Economides MK, McIntyre SK, Alam TM, Tartis MS, Werner-Washburne M, Brinker JC, Brozik SM, Wheeler DR. Encapsulation of S. cerevisiae in Poly(glycerol) Silicate Derived Matrices: Effect of Matrix Additives and Cell Metabolic Phase on Long-Term Viability and Rate of Gene Expression. Chemistry of Materials. Chem. Mater., 2011, 23 (10), pp 2555-2564.

Gupta G, Rathod S, Staggs K, Ista L, Abbou Oucherif K, Atanassov P, Tartis MS, Montano G, Lopez, G. CVD for Facile Synthesis of Hybrid Nano-Biomaterials Integrating Functional Supramolecular Assemblies. Langmuir. 2009 Dec 1;25(23):13322-7

Tartis MS, Kruse DE, Zheng H, Zhang H, Marik J, Kheirolomoom A, Ferrara KW. Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. J Control Release. 2008 131:160-166.

Marik J, Tartis MS, Zhang H, Fung JY, Kheirolomoom A, Sutcliffe JL, Ferrara KW. Long-circulating liposomes radiolabeled with [18F]fluorodipalmitin ([18F]FDP). Nucl Med Biol. 2007 Feb;34(2):165-71.

Tartis MS, McCallan J, LaBell R, Stieger SM, Matsunaga TO, Ferrara KW. Therapeutic effects of paclitaxel-containing ultrasound contrast agents. Ultrasound Med Biol. 2006 Nov;32(11):1771-80.

Shortencarier MJ, Dayton PA, LaBell R, Schumann PA, Matsunaga TO, Ferrara KW. Targeted chemotherapy delivery with ultrasound. Proceedings of the 2005 IEEE Ultrasonics Symposium (Sept 18 -21 Session 2C-2)

Shortencarier MJ, Dayton PA, Bloch SH, Schumann PA, Matsunaga TO, Ferrara KW. A method for radiation-force localized drug delivery using gas-filled lipospheres. IEEE Trans Ultrason Ferroelectr Freq Control. 2004 Jul;51(7):822-31.

Abstracts, Presentations, and Posters

Johsnton R, Rogelj S, Harper J, Tartis MS. Cellular Silica Encapsulation for the Development of Robust Cell Based Sensors. INBRE Symposium, Santa Fe, NM, 03/2015. Oral Presentation

Hunt A, Johnston R, Rogelj S, Tartis M. Transfection of Yeast Cells in Suspension using Ultrasound. INBRE Symposium, Santa Fe, NM, 03/2015. Poster Presentation 1st Place Award (all student posters)

Sanchez K, Marquez M, Myers M, Smith C, Johnston T, Frolova L, Rogelj S, Tartis M. Comparison of two anti-cancer lipid prodrugs in liposomes for targeted drug delivery. INBRE Symposium, Santa Fe, NM, 03/2015. Poster Presentation

Marquez M, Sanchez K, Johnston R, Rogelj S, Frolova L, Tartis M. Synthesis of Double Tail Analogues of Insoluble Chemotherapeutic Agents to Facilitate Incorporation into Drug Delivery Vehicles INBRE Symposium, Santa Fe, NM, 03/2015. Poster Presentation

Hunt A, Marquez M, Johnston R, Piyasena M, Tartis M. Ultrasound Mediated Transfection of Yeast for Bio-sensing Applications. American Institute of Chemical Engineering National Fall Conference. Atlanta, GA 11/2014. Poster Presentation

Sanchez K, Marquez M, Mikhalin A, Frolova L, Tartis M. Lipid Based Drug Delivery Vehicles for Targeted Drug Delivery. Alliance for Minority Participation Annual Conference, Las Cruces, NM 10/2014. Poster Presentation 2nd place Award

Johsnton R, Rogelj S, Harper J, Tartis MS. Cellular Silica Encapsulation for the Development of Robust Cell Based Sensors. American Physical Society. Annual Meeting, Denver, CO 3/2014. Oral Presentation

Marquez M, Sanchez K, Myers M, Hunt A, Mikhalin A, Johnston R, Rogelj S, Tartis M. Rigidin-like Prodrug loaded liposomes for targeted drug delivery. NMT Student Research Symposium Socorro, NM, 03/2014. Poster Presentation

Hunt A, Marquez M, Johnston R, Tartis M. Ultrasound Mediated Transfection: Sonoporation. NMT Student Research Symposium Socorro, NM, 03/2014. Poster Presentation

Johnston R, Rogelj S, Harper J, Tartis MS. Silica encapsulation of Saccharomyces cerevisiae for development of a robust cell-based biosensor. American Society of Cell Biology Annual Meeting, New Orleans, 12/2013. Poster Presentation

Myers M, Marquez M, Hunt A, Mikhalin A, Johnston R, Rogelj S, Tartis M. Microbubble formulations containing a dihydropyridopyrazole lipid prodrug: effects on biological activity after exposure to ultrasound. American Society of Cell Biology Annual Meeting, New Orleans, 12/2013. Poster Presentation

Marquez M, Myers M, Hunt A, Mikhalin A, Johnston R, Rogelj S, Tartis M. Prodrug loaded microbubbles for local ultrasound mediated delivery. Alliance for Minority Participation Annual Conference, Las Cruces, NM 10/2013. Poster Presentation

Johnston R, Larkin E, Erickson A, Rogelj S, Harper J, Tartis MS. Encapsulation of MicroOrganisms in Silica: Steps Toward a Robust Cell-Based Biosensor. NMT Student Research Symposium Socorro, NM, 03/2013. Oral Presentation

Tartis MS. Targeted delivery of chemotherapeutics using lipid carriers and ultrasound. INBRE Symposium, Santa Fe, NM, 03/2013 Oral Presentation

Johnston R, Larkin E, Erickson A, Rogelj S, Harper J, Tartis MS. Encapsulation of MicroOrganisms in Silica: Steps Toward a Robust Cell-Based Biosensor. NMT Student Research Symposium Socorro, NM, 03/2013. Oral Presentation

Mikhalin A, Rogelj S, Evdokimov N, Frolova L, Magedov I, Kornienko A, Tartis MS. Cellular uptake of dihydropyridopyrazole loaded liposomes and early induction of necrosis in Jurkat cells. INBRE Symposium, Santa Fe, NM, 03/2013. Poster Presentation

Johnston R, Larkin E, Erickson A, Rogelj S, Harper J, Tartis MS. Encapsulation of MicroOrganisms in Silica: Steps Toward a Robust Cell-Based Biosensor. INBRE Symposium, Santa Fe, NM, 03/2013. Poster Presentation

Myers M, Mikhalin A, Evdokimo N, Magedov I, Kornienko A, Rogelj S, Tartis MS. Microbubble formulations containing dihydropyridopyrazole for drug delivery. INBRE Symposium, Santa Fe, NM, 03/2013. Poster Presentation

Mikhalin A, Rogelj S, Evdokimov N, Frolova L, Magedov I, Kornienko A, Tartis MS. Podophyllotoxin-mimetic Analogues for Liposomal Drug Delivery. INBRE Symposium, Santa Fe, NM, 03/2012. Poster Presentation

Myers M, Mikhalin A, Evdokimo N, Magedov I, Kornienko A, Rogelj S, Tartis MS. Physiochemical Characterization of Microbubble as Vehicles for Targeted Drug Delivery. INBRE Symposium, Santa Fe, NM, 03/2012. Poster Presentation

Johnston R, Larkin E, Erickson A, Rogelj S, Harper J, Tartis MS. Encapsulation of Yeast in Silica: Steps Toward a Robust Cell-Based Biosensor. INBRE Symposium, Santa Fe, NM, 03/2012. Poster Presentation

Myers M, Mikhalin A, Evdokimo N, Magedov I, Kornienko A, Rogelj S, Tartis MS. Characterization of Microbubbles as Drug Delivery Vehicles in Cancer Therapy. NMSU NM-AMP Symposium, Las Cruces, NM, 10/2012. Poster Presentation

Tartis MS. Targeted delivery of chemotherapeutics using lipid carriers and ultrasound. INBRE Symposium, Santa Fe, NM, 03/2011. Oral Presentation

Gansz J, Mikhalin A, Evdokimov N, Magedov I, Kornienko A, Rogelj S, Tartis MS. Materials Characterization for the Design of Pro-Drug Containing Liposomes. INBRE Symposium, Santa Fe, NM, 03/2011. Poster Presentation

Mikhalin A, Rogelj S, Evdokimov N, Frolova L, Magedov I, Kornienko A, Tartis MS. Liposomal Incorporation of Myristic and Palmitic Podophyllotoxin Analogue Conjugates for Drug Delivery. INBRE Symposium, Santa Fe, NM, 03/2011. Poster Presentation

Aguilar M, Carpio L, Myers M, Mikhalin A, Evdokimo N, Magedov I, Kornienko A, Rogelj S, Tartis MS. Characterization of Microbubble Drug Delivery Vehicles. INBRE Symposium, Santa Fe, NM, 03/2011. Poster Presentation

Johnston R, Luchetti G, Magedov I, Kornienko A, Tartis MS, Rogelj S. The Effects of the Natural Compound ZR2. INBRE Symposium, Santa Fe, NM, 03/2011. Poster Presentation

Malik I, Hayden K, Frolova L, Daly S, Tartis MS, Kornienko A, Magedov I, Rogelj S. A Novel Bactericidal Compound with Biofilm-growth Inhibitory and DNA-damaging Activity. INBRE Symposium, Santa Fe, NM, 03/2011. Poster Presentation

Tartis MS. Targeted delivery of chemotherapeutics using lipid carriers and ultrasound. INBRE Symposium, Santa Fe, NM, 03/2010. Oral Presentation

Larkin E, Hahn M, Gansz J, Carpio L, Romero A, Staggs K, Lopez G, Kornienko A, Rogelj S, Tartis MS. Sample preparation techniques for biological samples in scanning electron microscopy: drug delivery. INBRE Symposium, Santa Fe, NM, 03/2010. Poster Presentation

Rose A, Larkin E, Myers M, Staggs K, Lopez G, Romero A, Kornienko A, Tartis MS. Microbubbles for drug delivery: effects of gas core composition, drug incorporation and silica deposition. INBRE Symposium, Santa Fe, NM, 03/2010. Poster Presentation

Mikhalin A, Allen C, Myers M, Romero A, Kornienko A, Rogelj S, Tartis M. Purification of drug conjugated liposomes by spin column size exclusion chromatography. INBRE Symposium, Santa Fe, NM, 03/2010. Poster Presentation

Larkin EC, Hahn M, Gansz J, Carpio L, Romero A, Staggs K, Lopez G, Kornienko A, Rogelj S, Tartis MS. Sample preparation techniques for biological samples in scanning electron microscopy: drug delivery. Texas Tech University of Health Sciences Symposium, Lubbock, TX, 03/2010. Poster Presentation

Cheng J, Gonzalez G, Romero A, Martinelli G, Kornienko A, Rogelj S, Tartis MS. Incorporating Singled-tailed Analogues of Anticancer compound Podophyllotoxin into liposome vehicles to investigate encapsulation capability and targeted delivery. SACNAS Conference, Dallas, TX, October 2009. Poster Presentation

Tartis MS, Kruse DE, Zheng H, Zhang H, Marik J, Kheirolomoom A, Ferrara KW. Microbubble Biodistribution and Targeted Drug Delivery. 83rd ACS Colloid & Surface Science Symposium, 13th IACIS International Conference on Surface and Colloid Science. June 14-19, 2009 New York, NY. Oral presentation

Tartis MS, Abbou-Oucherif K, Burch E. Taylor D, Rogelj S. In vitro delivery of hydrophobic drug particles without stabilizers: Practical implications. Gordon Research Conference: Drug Carriers in Medicine & Biology. August 24-29, 2008 Big Sky, MT. Poster Presentation.

Tartis MS, Kruse DE, Zheng H, Zhang H, Marik J, Kheirolomoom A, Ferrara KW. Ultrasound contrast agents: biodistribution and targeted delivery. Proceedings of the 2007 IEEE International Ultrasonics Symposium. Oct: 646.

Pollard RE, Tartis MS, Stern J, Bennett S, Ferrara KW. Contrast enhanced destruction-replenishment CPS ultrasound for cortical and medullary blood flow in a rat kidney model. Contrast Media Research. October, 2007.

Tartis MS, Marik J, Kheirolomoom A, Pollard RE, Zhang H, Qi J, Sutcliffe JL, Ferrara, KW. Pharmacokinetics of encapsulated paclitaxel: multi-probe analysis with PET. Proceedings of the ASME 2007 Summer Bioengineering Conference. June: 31.

Tartis MS. Finding your Research Path. NIBIB Diversity Training Workshop. Summer Bioengineering Conference. June 2007

Tartis MS, Marik J, Kheirolomoom A, Pollard RE, Zhang H, Qi J, Sutcliffe JL, Ferrara, KW. Pharmacokinetics of encapsulated paclitaxel: multi-probe analysis with PET. Mol Imaging. 2006 July;5(3):427-428.

Marik J, Zhang H, Tartis MS, Kheirolomoom A, Sutcliffe JL, Ferrara KW. Synthesis of 18F radiolabeled lipid and examples of its application. Mol Imaging. 2006 July;5(3):366.

Shortencarier MJ, Matsunaga TO, Schumann PA, LaBell R, Ferrara KW. Targeted Chemotherapy Delivery with Ultrasound. Proceedings of the 2005 IEEE International Ultrasonics Symposium. Sept:213-214.

Marik J, Shortencarier M, Pollard R, Johnson J, Matsunaga T, Kruse D, Ferrara KW, Sutcliffe-Goulden J. [F-18]Fluoropaclitaxel-containing vehicles for ultrasound-enhanced drug delivery. Imaging in 2020 IV. September, 2005.

Shortencarier MJ, McCallan J, Marik J, Pollard R, Stieger SM, Johnson J, Matsunaga TO, Kruse D, Ferrara KW. Imaging ultrasound enhancement of drug delivery: efficacy and biodistribution. Mol Imaging. 2005 Jul-Sept;4(3):367-368.

Shortencarier MJ, Dayton PA, Bloch SH, Schumann PA, LaBell R, Matsunaga TO, Ferrara KW. A new targeted imaging and drug delivery method using ultrasound and acoustically active lipospheres. Journal of the Acoustic Society of America Meeting. 2005 April;117(4):2473.

Shortencarier MJ, Dayton PA, Bloch SH, Schumann PA, LaBell R, Matsunaga TO, Ferrara KW. A new targeted imaging and drug delivery method using ultrasound and acoustically active lipospheres. Tenth Annual Cancer Research Symposium. 2004:49.

Shortencarier MJ, Dayton PA, Bloch SH, Schumann PA, LaBell R, Matsunaga TO, Ferrara KW. A new targeted imaging and drug delivery method using ultrasound and acoustically active lipospheres. Mol Imaging. 2004 Jul;3(3):273.

Unger EC, Zutshi R, LaBell R, Schumann PA, Dayton PA, Shortencarier M, Bloch S, Ferrara K, Matsunaga TO. Overcoming biological barriers with acoustically active carriers and ultrasound. Mol Imaging. 2004 Jul;3(3):203.

Shortencarier MJ, Dayton PA, Pearson D, Schumann PA, Zutshi R, Matsunaga TO, Ferrara KW. Ultrasound radiation force on acoustically-active lipospheres for drug delivery. Proceedings of the 2003 IEEE International Ultrasonics Symposium. Oct: 73-74, 400.

Professional Memberships

* Society of Molecular Imaging
* IEEE Ultrasound, Ferroelectronics, and Frequency Control
* Advancing Hispanics/Chicanos & Native Americans in Science (SACNAS)

Honors and Awards

*Outstanding Faculty Award, New Mexico Tech President, 2010-2011
*Distinguished Faculty Award, AIChE Student Chapter, 2008-2009, 2010-2011
*Invited Speaker, NIBIB Diversity Training Workshop prior to ASME's Summer Bioengineering Conference, 2007
*Achievement Rewards for College Scientist Scholar, UC Davis 2005
*NIH Training Grant Trainee, UC Davis 2005 - 2006
*Awarded travel funds to four international conferences based on abstract submission, 2005-2006
*Best Poster Award, UCD Medical Center Cancer Symposium, 2004
*Student paper finalist, IEEE Ultrasonics Symposium 2003
*NIH-IMSD Fellowship 2003 - 2005
*Kramer Award (Highest GPA in graduating class), New Mexico Tech 2002
*Student Appreciation Award, New Mexico Tech 2001