Snena Rogelj
Professor of Biology
New Mexico Tech
801 Leroy Pl., Socorro, NM 87801
Phone: (575) 835-5608
FAX: (575) 835-5668
E-mail: snezna@nmt.edu
Published by the Biology Department, Jones Annex, NM Tech, 801 Leroy Place, Socorro, NM, 87801 (575) 835-5612
Peer-reviewed Publications
(34 peer-reviewed publications, over 3200 citations in peer-reviewed journals)
[1] S. Rogelj, B. Loewy and R.M. Niles: The Effect of Retinoic Acid on Cyclic AMP Binding Proteins in Mouse Melanoma Cells. European Journal of Biochemistry 139: 351-357 (1984).
[2] R.M. Niles, B. Loewy and S. Rogelj: The Effect of Retinoic acid on Protein Phosphorylation in Mouse Melanoma Cells. Experimental Cell Research 164: 437-44 (1986).
[3] S.H. Friend, R. Bernards, S. Rogelj, R.A. Weinberg, J.M. Rappaport, D.M. Albert and T.P. Dryja: Identification of a Human DNA Segment Having Properties of the Gene that Predisposes to Retinoblastoma and Osteosarcoma. Nature, 323(6089): 643-646 (1986).
[4] S. Rogelj, R.A. Weinberg, P. Fanning and M. Klagsbrun: Basic Fibroblast Growth Factor (bFGF) Fused to a Signal Peptide Transforms Cells. Nature, 331(6152): 173-175 (1988).
[5] R. Hannan, S. Kourembans, K. Flanders, S. Rogelj, A. Roberts, D. Faller and M. Klagsbrun: Human Endothelial Cells Synthesize Fibroblast Growth Factor and Transforming Growth Factor Beta. Growth Factors, 1: 7-17 (1988).
[6] S. Rogelj, R.A. Weinberg, P. Fanning and M. Klagsbrun: Characterization of Tumors Produced by Signal Peptide-bFGF Transformed Cells. Journal of Cellular Biochemistry 39: 13-24(1989).
[7] S. Rogelj, M. Klagsbrun, R. Atzmon, M. Kurokawa, A.Haimovitz, Z. Fuks and I. Vlodavsky: Basic fibroblast growth required for supporting the proliferation of vascular endothelial cells and the differentiation of PC-12 cells. Journal of Cell Biology, 109: 823-831 (1989).
[8] N. Iberg, S. Rogelj, P. Fanning and M. Klagsbrun: Purification of 18 kDa and 22 kDa forms of basic fibroblast growth factor in cells transformed by the ras oncogene. Journal of Biological Chemistry, 264 (33): 19951-19955 (1989).
[9] S.E. Egan, L. Jarolim, S. Rogelj, M. Spearman, J.A. Wright and A.H. Greenberg: Growth Factor Modulation of Metastatic Lung Colonization. Anticancer Research 10: 1341-1346 (1990).
[10] W.E.Serafin, D.S.Reynolds, S.Rogelj, W.S.Lane, G.Conder, S.S.Johnson, K.F.Austen and R.L.Stevens: Identification and Molecular Cloning of a Novel Mouse Mucosal Mast Cell Serine Protease. Journal of Biological Chemistry 265(1): 423-429 (1990).
[11] Goldstein B., Rogelj S., Siegal S., Farmer S.R., Niles R.M.: Cyclic AMP mediated induction of F9 teratocarcinoma differentiation in the absence of retinoic acid. Journal of Cellular Physiology 143(2):205-212 (1990).
[12] Bennett T.A., Schammel C.M.G., Lynam E.B., Guyer D.A., Mellors A., Edwards B., Rogelj S. and Sklar L.A.: Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures Journal of Leukocyte Biology 58: 510-518 (1995).
[13] Bennett T.A., E.B. Lynam, Sklar L.A. and Rogelj S.: Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation. Journal of Immunology 156: 3093-3097 (1996).
[14] Lynam E.B., Rogelj S., Edwards, B.S. and Sklar, L.A.: Enhanced aggregation in human neutrophils by MnCl2 or DTT differentiates the roles of L-selectin and beta2-integrins. Journal of Leukocyte Biology 60: 356-364, (1996).
[15] Guyer D.A., Moore K., Schammel C.M.G., Lynam E., Bennett T., Rogelj S, Edwards B.S., Mellors A., McEver R., and Sklar, L.A.: P-Selectin Glycoprotein Ligand-1(PSGL-1) is a Ligand for L-selectin in Neutrophil Aggregation. Blood 88:(7) 2415-2421 (1996).
[16] Bennett T.A., Edwards,B.S., Sklar L.A. and Rogelj S.: Sulfhydryl Regulation of L-Selectin: Promotion of Activation Independent L-selectin Shedding from Leukocytes. Journal of Immunology 164:4120-4129 (2000).
[17] Rogelj S., Reiter K.J., Kesner L., Li M. and Essex D.: Enzyme Destruction by a Protease Contaminant in Bacitracin. Biochemical and Biophysical Research Communications. 273(3):829-832 (2000).
[18] Liang H., Cordova SE., Kieft TL., Rogelj S. "A highly sensitive immuno-PCR assay for detecting Group A Streptococcus" Journal of Immunological Methods. 279(1-2):101-10 (2003).
[19] Fu, Z., S. Rogelj, and T. L. Kieft "Detection of Escherichia coli O157:H7 by immuno-magnetic separation and real-time PCR" International Journal of Food Microbiology. 99: 47-57 (2005)
[20] Shen K., Curran S., Xu H., Rogelj S., Jiang Y., Dewald J., and Pietraß T. "Single-walled carbon nanotube purification, pelletizing and surfactant-assisted dispersion: A combined TEM and resonant micro-Raman spectroscopy study". The Journal of Physical Chemistry B. 109:4455-4463 (2005)
[21] Shen, H., Rogelj, S., and T. L. Kieft "Sensitive, Real-time PCR Detects Low-levels of Contamination by Legionella pneumophila in Commercial Reagents". Molecular and Cellular Probes. 20(3-4 " target="_blank"><http://www.sciencedirect.com/science?_ob=PublicationURL&_tockey=%23TOC%236959%232006%23999799996%23622514%23FLA%23&_cdi=6959&_pubType=J&view=c&_auth=y&_acct=C000054882&_version=1&_urlVersion=0&_userid=1818435&md5=395fba61e2bd578d9d872474f114af0d>):147-153 (2006)
[22] Allen R.C.; Rogelj, S., Cordova, S.E., and T. L. Kieft. "An Immuno-PCR Method for Detecting Bacillus thuringiensis Cry1Ac Toxin" Journal of Immunological Methods. 20(3-4): 147-153 (2006).
[23] A. S. Kireev, O. N. Nadein, V. J. Agustin, N. E. Bush, A. Evidente, M. Manpadi, M. A. Ogasawara, S. K. Rastogi, S. Rogelj, S.T. Shors, A. Kornienko. "Synthesis and Biological Evaluation of Aromatic Analogues of Conduritol F, L-chiro-Inositol and Dihydroconduritol F Structurally Related to the Amaryllidaceae Anticancer Constituents" Journal of Organic Chemistry 71, 5694-5707 (2006).
[24] Zhang P, S. Rogelj, K. Nguyen, and D. Wheeler. Design of a Highly Sensitive and Specific Nucleotide Sensor Based on Photon Upconverting Particles. Journal of American Chemical Society 128 (38), 12410 -12411 (2006)
[25] Magedov, I. V.; Manpadi, M.; Rozhkova, E.; Przhevalískii, N. M.; Rogelj, S.; Shors, S. T.; Steelant, W. F. A.; Van slambrouck, S. and A. Kornienko. Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis: Dihydropyridopyrazole Analogues of Podophyllotoxin. Bioorganic and Medicinal Chemistry Letters 17, 1381-1385 (2007)
[26] Magedov, I. V.; Manpadi, M.; Evdokimov, N. M.; Elias, E. M.; Rozhkova, E.; Ogasawara, M. A.; Bettale, J. D.; Przhevalískii, N. M.; Rogelj, S.; Kornienko, A. Antiproliferative and apoptosis inducing properties of pyrano[3,2-c]pyridones accessible by a one-step multicomponent synthesis. Bioorganic and Medicinal Chemistry Letters 17, 3872-3876 (2007)
[27] Magedov, I.V.; Manpadi, M.; Van Slambrouck, S.; Steelant, W. F. A.; Rozhkova, E.; Przhevalískii, N. M.; Rogelj, S.; Kornienko, A. Discovery and Investigation of Antiproliferative and Apoptosis-Inducing Properties of New Heterocyclic Podophyllotoxin Analogues Accessible by a One-Step Multicomponent Synthesis. Journal of Medicinal Chemistry 50, 5183-5192 (2007)
[28] Manpadi, M.; Uglinskii, P. Y.; Rastogi, S. K.; Cotter, K. M.; Wong, Y-S. C.; Anderson, L. A.; Ortega, A. J.; Van slambrouck, S.; Steelant, W. F. A.; Rogelj, S.; Tongwa, P.; Antipin, M. Y.; Magedov, I. V.; Kornienko, A. Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties. Organic & Biomolecular Chemistry . 5, 3865 - 3872 (2007)
[29] Magedov, I. V.; Manpadi, M.; Ogasawara, M. A.; Dhawan, A. S.; Rogelj, S.; Van slambrouck, S.; Steelant, W. F. A.; Evdokimov, N. M.; Uglinskii, P. Y.; Elias, E. M.; Knee, E. J.; Tongwa, P.; Antipin, M. Y.; Kornienko, A. Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones. Journal of Medicinal Chemistry 51, 2561-2570 (2008)
[30] Guo Y., Rogelj S. and Zhang, P. Rose Bengal-decorated silica nanoparticles as photosensitizers for inactivation of gram-positive bacteria. Nanotechnology. 21 (2010) 065102. doi:10.1088/0957-4484/21/6/065102
[31 ] Tang, H., Zhang, P., Kieft, T.L., Ryan, S.J., Baker, S.M., Wiesmann, W.P., Rogelj, S. Antibacterial action of a novel functionalized chitosan-arginine against gram-negative bacteria, Acta Biomaterialia 6(7) 2562-2571 (2010)
[32] Evdokimov, N. M.; Van slambrouck, S.; Heffeter, P.; Tu, L.; Le Calve, B.; Lamoral-Theys, D.; Hooten, C. J.; Uglinskii, P. Y.; Rogelj, S.; Kiss, R.; Steelant, W. F. A.; Berger, W.; Yang, J. J.; Bologa, C. J.; Kornienko, A.; Magedov, I. V. Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 3. Fused Uracil-Containing Heterocycles as Novel Topoisomerase-Targeting Agents. Journal of Medicinal Chemistry 54, 2012 -2021 (2011)
[33] Frolova, L. V.; Evdokimov, N. M.; Hayden, K.; Malik, I.; Rogelj, S.; Kornienko, A.; Magedov, I. V. One-Pot Multicomponent Synthesis of Diversely Substituted 2-Aminopyrroles. A short General Synthesis of Rigidins A, B, C, and D. Organic Letters. 13, 1118-1121 (2011)
[34] Magedov, I.; Frolova, L.; Manpadi, M.; Bhoga, U.; van Otterlo, W.; Tang, H.; Evdokimov, N.; George, O.; Hadji Gorgeou, K.; Renner, S.; Getlik, M.; Kinnibrugh, T.; Fernandes, M.; Van slambrouck, S.; Shuster, C.; Rogelj, S.; Steelant, W.; Kornienko, A.: Anticancer Properties of an Important Drug Lead Podophyllotoxin Can Be Efficiently Mimicked by Diverse Heterocyclic Scaffolds Accessible via One-Step Synthesis. Journal of Medicinal Chemistry 54(12):4234-4246 (2011)
[35] Seth Daly , Kathryn Hayden, Indranil Malik, Nikki Porch, Hong Tang, Snezna Rogelj, Liliya V. Frolova, Katrina Lepthien, Alexander Kornienko, and Igor V. Magedov.: Unprecedented C-2 Arylation of Indole with Diazonium Salts: Syntheses of 2,3-Disubstituted Indoles and their Antimicrobial Activity. Bioorganic & Medicinal Chemistry Letters 21(16) 4720-4723 (2011)
[36] Liliya V. Frolova, Nikolai M. Evdokimov, Kathryn Hayden, Indranil Malik, Snezna Rogelj, Alexander Kornienko, and Igor V. Magedov One-Pot Multicomponent Synthesis of Diversely Substituted 2-Aminopyrroles. A Short General Synthesis of Rigidins A, B, C, and D. Organic Letters 13 (5), pp 1118-1121 (2011)
[37] L. V. Frolova, N. M. Evdokimov, K. Hayden, I. Malik, S. Rogelj, A. Kornienko, I. V. Magedov: Synthesis of Polysubstituted 2-Aminopyrroles via a Multicomponent Reaction. Organic Letters 13, 1118-1121 (2011)
[38] Frolova LV, Malik I, Uglinskii PY, Rogelj S, Kornienko A, Magedov IV.: Multicomponent Synthesis of 2,3-Dihydrochromeno[4,3-d]pyrazolo[3,4-b]pyridine-1,6-diones: A Novel Heterocyclic Scaffold with Antibacterial Activity. Tetrahedron Lett. 2011 Dec 7;52(49):6643-6645
[39] Giovanni Luchetti, Robert Johnston, Véronique Mathieu, Florence Lefranc, Kathryn Hayden, Anna Andolfi, Delphine Lamoral-Theys, Mary R. Reisenauer, Cody Champion, Stephen C. Pelly, Willem A. L. van Otterlo, Igor V. Magedov, Robert Kiss, Antonio Evidente, Snezna Rogelj, and Alexander Kornienko.: Bulbispermine: A Crinine-Type Amaryllidaceae Alkaloid Exhibiting Cytostatic Activity towards Apoptosis-Resistant Glioma Cells. ChemMedChem. (Accepted Jan 2012)
Book Contributions:
[1] S. Rogelj and M. Klagsbrun: Basic Fibroblast Growth Factor Induces Tumorigenicity in Immunocompetent Animals Only After Acquiring a Signal Peptide. Progress in Endocrinology, 517-522. Imura et al., editors. Elsevier Science Publishers B.V., Biomedical Division (1988)
[2] S. Rogelj and M. Klagsbrun: Oncogenic Transformation by Basic Fibroblast Growth Factors. In: Paracrine and Autocrine Factors in Reproductive Endocrinology, p.19-28. Bela J. Gulyas and Lewis C. Krey, eds. Plenum Press (1989)
[3] M. Klagsbrun, P. Fanning and S. Rogelj: Ras Transformation in 3T3 cells induces fibroblast growth factor synthesis in vitro and in vivo. In: Molecular Mechanisms in Cellular Growth and Differentiation. P&S Biomedical Sciences Symposia (1989)
[4] S. Rogelj, D.F. Stern and M. Klagsbrun: Construction and Expression of a Transforming Gene Resulting From a Fusion of a Basic FGF Gene with a Signal Peptide Sequence. In: Peptide Growth Factors, Methods in Enzymology, 198 , 117-124. D. Barnes, J.P. Mather and G.H. Sato, eds. Academic Press (1991)
