PUBLICATIONS

Chemistry, Biology, and Medicinal Potential of Narciclasine and its Congeners. Kornienko, A.; Evidente, A. Chem. Rev. 2008, in press.

Evaluation of aqueous extracts of Taraxacum officinale on growth and invasion of breast and prostate cancer cells. Sigstedt, S. C.; Hooten, C. J.; Callewaert, M. C.; Jenkins, A. R.; Romero, A. E.; Pullin, M. J.; Kornienko, A.; Lowrey, T. K.; Van slambrouck, S.; Steelant, W. F. A. Int. J. Oncol. 2008, 32, 1085.

Total Syntheses of Pancratistatin. Manpadi, M.; Kornienko, A. Org. Prep. Proced. Int. 2008, 40, 107.

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis. 2. Antiproliferative and Antitubulin Activities of Pyrano[3,2-c]pyridones and Pyrano[3,2-c]quinolones. Magedov, I. V.; Manpadi, M.; Ogasawara, M. A.; Dhawan, A. S.; Rogelj, S.; Van slambrouck, S.; Steelant, W. F. A.; Evdokimov, N. M.; Uglinskii, P. Y.; Elias, E. M.; Knee, E. J.; Tongwa, P.; Antipin, M. Y.; Kornienko, A. J. Med. Chem. 2008, 51, 2561.

Novel Three-Component Synthesis and Antiproliferative Properties of Diversely Functionalized Pyrrolines. Magedov, I. V.; Luchetti, G.; Evdokimov, N. M.; Manpadi, M.; Steelant, W. F. A.; Van slambrouck, S.; Tongwa, P.; Antipin, M. Y.; Kornienko, A. Bioorg. Med. Chem. Lett. 2008, 18, 1392.

Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties. Manpadi, M.; Uglinskii, P. Y.; Rastogi, S. K.; Cotter, K. M.; Wong, Y-S. C.; Anderson, L. A.; Ortega, A. J.; Van slambrouck, S.; Steelant, W. F. A.; Rogelj, S.; Tongwa, P.; Antipin, M. Y.; Magedov, I. V.; Kornienko, A. Org. Biomol. Chem. 2007, 5, 3865.

Discovery and Investigation of Antiproliferative and Apoptosis-Inducing Properties of New Heterocyclic Podophyllotoxin Analogues Accessible by a One-Step Multicomponent Synthesis. Magedov, I.V.; Manpadi, M.; Van Slambrouck, S.; Steelant, W. F. A.; Rozhkova, E.; Przhevalískii, N. M.; Rogelj, S.; Kornienko, A. J. Med. Chem. 2007, 50, 5183.

Antiproliferative and apoptosis inducing properties of pyrano[3,2-c]pyridones accessible by a one-step multicomponent synthesis. Magedov, I. V.; Manpadi, M.; Evdokimov, N. M.; Elias, E. M.; Rozhkova, E.; Ogasawara, M. A.; Bettale, J. D.; Przeval’skii, N. M.; Rogelj, S.; Kornienko, A. Bioorg. Med. Chem. Lett. 2007, 17, 3872.

One-Step Synthesis of Heterocyclic Privileged Medicinal Scaffolds Using a Multicomponent Reaction of Malononitrile with Aldehydes and Thiols. Evdokimov, N. M; Kireev, A. S.; Yakovenko, A. A.; Antipin, M. Y.; Magedov, I. V.; Kornienko, A. J. Org. Chem. 2007, 5, 3865.

Effects of crude aqueous Medicinal Plant Extracts on growth and invasion of breast cancer cells. Van slambrouck, S.; Daniels, A. L.; Hooten, C. J.; Brock, S. L.; Jenkins A. R.; Ogasawara M. A.; Baker, J. M.; Adkins G.; Elias E. M.; Agustin, V. J.; Constantine, S. R.; Pullin, M. J.; Shors, S. T.; Kornienko, A.; Steelant, W. F. A. Oncology Reports, 2007, 17, 1487.

Structural Simplification of Bioactive Natural Products with Multicomponent Synthesis: Dihydropyridopyrazole Analogues of Podophyllotoxin. Magedov, I. V.; Manpadi, M.; Rozhkova, E.; Przheval’skii, N. M.; Rogelj, S.; Shors, S. T.; Steelant, W. F. A.; Van slambrouck, S.; Kornienko, A. Bioorg. Med. Chem. Lett. 2007, 17, 1381.

A solution to the stereochemical problems posed by amaryllidaceae constituents using a highly syn-selective arylcuprate conjugate addition to g-amino and g-carbamato-a,b-enoates. Rastogi, S. K.; Kornienko, A. Tetrahedron: Asymmetry, 2006, 13, 3170.

Convenient One-Step Synthesis of a Medicinally Relevant Benzopyranopyridine System. Evdokimov, N. M; Kireev, A. S.; Yakovenko, A. A.; Antipin, M. Y.; Magedov, I. V.; Kornienko, A. Tetrahedron Lett. 2006, 47, 9309.

Synthesis and Biological Evaluation of Aromatic Analogues of Conduritol F, L-chiro-Inositol and Dihydroconduritol F Structurally Related to the Amaryllidaceae Anticancer Constituents. Kireev, A. S.; Nadein, O. N.; Agustin, V. J.; Bush, N. E.; Evidente, A.; Manpadi, M.; Ogasawara, M. A.; Rastogi, S. K.; Rogelj, S.; Shors, S. T.; Kornienko, A. J. Org. Chem. 2006, 71, 5694.

Effects of extracts from two Native American plants on proliferation of human breast and colon cancer cell lines in vitro. Daniels, A. L.; Van slambrouck, S.; Lee, R. L.; Arguello, T. S.; Browning, J.; Pullin, M. J.; Kornienko, A.; Steelant, W. F. A. Oncology Reports, 2006, 15, 1327.

Selectivity Guidelines and a Reductive Elimination-Based Model for Predicting the Stereochemical Course of Conjugate Addition Reactions of Organocuprates to g-Alkoxy-a,b-enoates. Kireev, A. S.; Manpadi, M.; Kornienko, A. J. Org. Chem. 2006, 71, 2630.

One Step Three-Component Synthesis of Pyridines and 1,4-Dihydropyridines with Manifold Medicinal Utility. Evdokimov, N.M.; Magedov, I. V.; Kireev, A. S.; Kornienko, A. Org. Lett. 2006, 8, 899.

Highly anti selective conjugate addition of arylcuprates to a g-alkoxy-a,b-enoate. A new method to address stereochemical challenges presented by Amaryllidaceae alkaloids. Manpadi, M.; Kornienko, A. Tetrahedron Lett. 2005, 46, 4433.

Enantiodivergent Formal Synthesis of (+)- and (-)-Cyclophellitol Based on the Latent Symmetry Concept. Kireev, A. S., Breithaupt, A. T.; Collins, W.; Nadein, O. N.; Kornienko, A. J. Org. Chem. 2005, 70, 742.

An Approach to Pancratistatins via Ring-Closing Metathesis: Efficient Synthesis of Novel 1-Aryl-1-deoxyconduritols F. Nadein, O. N.; Kornienko, A., Org. Lett. 2004, 6, 831.

Probing the functional requirements of the L-haba side-chain of amikacin – Synthesis, 16S A-Site rRNA binding, and antibacterial activity. Hanessian, S.; Kornienko, A.; Swayze, E. E., Tetrahedron 2003, 59, 995.

Design, modeling and synthesis of functionalized paromamine analogs. Hanessian, S.; Tremblay, M.; Kornienko, A.; Moitessier, N., Tetrahedron 2001, 57, 3255.

Synthesis of Cyclitols via Ring-Closing Metathesis. Kornienko, A.; d’Alarcao, M., Tetrahedron: Asymmetry 1999, 10, 827.

Practical Synthesis of a Differentially Protected myo-Inositol. Kornienko, A.; Turner, D. I.; Jaworek, C. H.; d’Alarcao, M., Tetrahedron: Asymmetry 1998, 9, 2783.

Synthesis of a Jojoba Bean Disaccharide. Kornienko, A.; Marnera, G.; d’Alarcao, M., Carbohydr. Res. 1998, 310, 141.

Enantiospecific Synthesis of a Differentially Protected L-chiro-Inositol from D-Xylose. Kornienko, A.; d’Alarcao, M., Tetrahedron Lett. 1997, 38, 6497.

A New Convenient Method to Obtain Pyrroles from Tertiary N-Allylthioamides. Magedov, I. V.; Kornienko, A. V.; Zotova, T. O.; Drozd, V. N., Tetrahedron Lett. 1995, 36, 4619.